4.7 Article

karyoploteR: an R/Bioconductor package to plot customizable genomes displaying arbitrary data

期刊

BIOINFORMATICS
卷 33, 期 19, 页码 3088-3090

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btx346

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资金

  1. Spanish Ministry of Science and Innovation, Carlos III Health Institute (ISCIII) [PI11/1609, PI14/00577, RTICC RD12/0036/008]
  2. FEDER program
  3. Government of Catalonia [2014 SGR 338]
  4. Spanish Association Against Cancer (AECC)

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Motivation: Data visualization is a crucial tool for data exploration, analysis and interpretation. For the visualization of genomic data there lacks a tool to create customizable non-circular plots of whole genomes from any species. Results: We have developed karyoploteR, an R/Bioconductor package to create linear chromosomal representations of any genome with genomic annotations and experimental data plotted along them. Plot creation process is inspired in R base graphics, with a main function creating karyoplots with no data and multiple additional functions, including custom functions written by the end-user, adding data and other graphical elements. This approach allows the creation of highly customizable plots from arbitrary data with complete freedomon data positioning and representation.

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