Functionalization of Carbonyl Compounds via Photoredox Organocatalysis

In recent years, a methodology merging photoredox catalysis with organocatalysis termed photoredox organocatalysis has emerged to allow the direct, selective and efficient functionalization of the alpha/beta-C of carbonyl compounds under mild reaction condition. In this review, photophysics background of photoredox catalysis is introduced, followed by a report on recent advances in direct alpha- and beta-functionalization of carbonyls with photoredox organocatalysis methodology. With this different reaction modes, valuable synthetic targets including different alpha/beta-functionalized carbonyls are accessible.