期刊
ACS CHEMICAL BIOLOGY
卷 12, 期 10, 页码 2510-2514出版社
AMER CHEMICAL SOC
DOI: 10.1021/acschembio.7b00348
关键词
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资金
- China Scholarship Council
- Netherlands Organization for Scientific Research program grant TOP-PUNT [13.006]
- ERC
- Netherlands Organization for Scientific Research Vidi grant [723.015.002]
Knowledge of the ionic strength In cells is required to understand the in vivo biochemistry of the charged biomacromolecules. Here, we present the first sensors to determine the ionic strength in living cells, by designing protein probes based on Forster resonance energy transfer (FIET). These probes allow observation of spatiotemporal changes in the;ionic strength on the single-cell level.
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