期刊
CHEMICAL RECORD
卷 17, 期 10, 页码 1019-1038出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.201600146
关键词
Imidazo [1, 2-a] pyridines; Intramolecular cyclization; Hydroamination; Regioselectivity; C-S bond formations
资金
- DST, Government of India [EMR/2016/000010]
- CSIR-CSMCRI [OLP-087]
Imidazo[1,2-a]pyridines play an important role in medicinal chemistry. In spite of very drastic developments on syntheses and functionalization in this area, the use of inexpensive catalysts and mild reaction conditions constitutes an important role in pharmaceutical applications. This account describes our recent efforts on the development of new methods for the synthesis of imidazo[1,2-a]pyridines using readily available starting substrates and catalysts under very mild reaction conditions. In the direction of enhancement of biological activity, we also described the synthesis of functionalized imidazo [1,2-a]pyridine derivatives.
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