期刊
CURRENT OPINION IN MICROBIOLOGY
卷 39, 期 -, 页码 81-88出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2017.09.010
关键词
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类别
资金
- Institut Pasteur
- Inserm
- INRA
- National Research Agency (ANR) [ERANET Infect-ERA PROANTILIS ANR-13-IFEC-0004-02]
- French Government's Investissement d'Avenir program
- Laboratoire d'Excellence 'Integrative Biology of Emerging Infectious Diseases' [ANR-10-LABX-62-IBEID]
- European Research Council (ERC) [H2020-ERC-2014-ADG 670823-BacCellEpi]
- Human Frontier Science Program Organization [RGP011/2013]
- Fondation le Roch les Mousquetaires
- Fondation Balzan
Small proteins, that is, polypeptides of 50 amino acids (aa) or less, are increasingly recognized as important regulators in bacteria. Secreted or not, their small size make them versatile proteins, involved in a wide range of processes. They may allow bacteria to sense and to respond to stresses, to send signals and communicate, and to modulate infections. Bacteriophages also produce small proteins to influence lysogeny/lysis decisions. In this review, we update the present view on small proteins functions, and discuss their possible applications.
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