期刊
ADVANCED MATERIALS
卷 29, 期 37, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201606596
关键词
biological barriers; drug delivery; transdermal transport
类别
资金
- Trailblazer Research Grant by Department of Anesthesia at Boston Children's Hospital
- Charles H. Hood Foundation Child Health Research Award
- [NIHDC015050]
The delivery of drugs to a target site frequently involves crossing biological barriers. The degree and nature of the impediment to flux, as well as the potential approaches to overcoming it, depend on the tissue, the drug, and numerous other factors. Here an overview of approaches that have been taken to crossing biological barriers is presented, with special attention to transdermal drug delivery. Technology and knowledge pertaining to addressing these issues in a variety of organs could have a significant clinical impact.
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