期刊
DEVELOPMENTAL CELL
卷 43, 期 2, 页码 124-140出版社
CELL PRESS
DOI: 10.1016/j.devcel.2017.09.016
关键词
-
资金
- EMBO [ALTF 1474-2016]
- longterm Human Science Frontier Program [LT000053/2017]
Over 600 million years ago, animals evolved from a unicellular or colonial organism whose cell(s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar collar. Using principles from evolutionary cell biology, we reason that the transition to multicellularity required modification of pre-existing mechanisms for extracellular matrix synthesis and cytokinesis. We discuss two hypotheses for the origin of animal cell types: division of labor from ancient plurifunctional cells and conversion of temporally alternating phenotypes into spatially juxtaposed cell types. Mechanistic studies in diverse animals and their relatives promise to deepen our understanding of animal origins and cell biology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据