期刊
CHEMICAL COMMUNICATIONS
卷 53, 期 75, 页码 10406-10409出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc06246j
关键词
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资金
- National Institutes of Health [GM111749]
The design and synthesis of compounds that target mixed, AT/GC, DNA sequences is described. The design concept connects two N-methyl-benzimidazole-thiophene single GC recognition units with a flexible linker that lets the compound fit the shape and twist of the DNA minor groove while covering a full turn of the double helix.
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