期刊
VISION RESEARCH
卷 139, 期 -, 页码 191-203出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.visres.2017.05.006
关键词
Retina; Imaging; Diabetic retinopathy; OCT; OCT angiography; Visible-light OCT
资金
- National Institutes of Health [DP3DK108248, R01EY026078, T32GM008152, F30EY026472]
In recent years, advances in optical coherence tomography (OCT) techniques have increased our understanding of diabetic retinopathy, an important microvascular complication of diabetes. OCT angiography is a non-invasive method that visualizes the retinal vasculature by detecting motion contrast from flowing blood. Visible-light OCT shows promise as a novel technique for quantifying retinal hypoxia by measuring the retinal oxygen delivery and metabolic rates. In this article, we discuss recent insights provided by these techniques into the vascular pathophysiology of diabetic retinopathy. The next milestones for these modalities are large multicenter studies to establish consensus on the most reliable and consistent outcome parameters to study diabetic retinopathy. (C) 2017 Elsevier Ltd. All rights reserved.
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