期刊
BIOSENSORS & BIOELECTRONICS
卷 97, 期 -, 页码 157-163出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2017.05.035
关键词
Carbon dots; Copper Electron transfer; Cellular imaging; Visual sensing
类别
资金
- Natural Science Foundation Project of China [21405123]
- Natural Science Foundation Project of Chongqing [cstc2014jcyjA50006]
- Fundamental Research Funds for the Central Universities [XDJK2016B039]
As an integral part of many important enzymes, Cu2+ is involved in a number of vital biological processes, which is linked to the oxidative damage and environmental contamination when Cu2+ is excessive. In this work, Cu2+ can be captured by the amino groups of carbon dots (CDs) to form complexes, resulting in a strong fluorescence quenching of CDs via a nonradiative electron transfer process, which offered a rapid, visual, and selective methodology for Cu2+ detection. The probe exhibited a wide response concentration range (0.01-2 mu M) to Cu2+ with a detection limit of 6.7 nM. Significantly, the CDs presented excellent biocompatibility and high photostability, which were applicable for the visualization of Cu2+ dynamic invasion into living cells and Tilapia mossambica. Furthermore, the toxicity of Cu2+ ions to living cells could be inhibited with CDs by the formation of complexes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据