期刊
ACTA TROPICA
卷 176, 期 -, 页码 224-227出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.actatropica.2017.08.015
关键词
Taenia hydatigena; Echinococcus granulosus; Metacestode; Cyst fluid
资金
- National Key Basic Research Program (973 program) of China [2015CB150300]
- National Natural Science Foundation of China [31201900, 31472185]
- Central State Public-interest Scientific Institution Basal Research Fund [1610312016017]
Taenia hydatigena is a parasitic flatworm that is widely distributed around the world. Using MS/MS, the proteome of T. hydatigena cyst fluid (CF) was profiled and a total of 520 proteins were identified, 430 of which were of sheep origin. T. hydatigena shared 37 parasite-origin and 109 host-origin CF proteins with Echinococcus granulosus. Compared with E. granulosus, T. hydatigena had much more CF proteins associated with amino acid synthesis and complement cascades. In addition, glutamate metabolism and anti-oxidative reactions were identified as relatively more important events. These results suggest that T. hydatigena metacestodes have internal microenvironment with special immune and oxidative conditions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据