期刊
BRITISH JOURNAL OF HEALTH PSYCHOLOGY
卷 22, 期 4, 页码 998-1018出版社
WILEY
DOI: 10.1111/bjhp.12274
关键词
adherence; breast cancer; common sense model; tamoxifen; theory of planned behaviour
资金
- Breast Cancer Now [2013NovPhD201]
ObjectivesTamoxifen non-adherence is apparent in up to half of breast cancer survivors and is associated with increased risk of recurrence and reduced quality of life. However, factors contributing to non-adherence in this population are currently poorly understood. This study explored the relationship between key components of the Common Sense Model of Illness Representations (CSM)/the Theory of Planned Behaviour (TPB) and intentional and unintentional non-adherence in a large sample of women prescribed tamoxifen following primary breast cancer. DesignCross-sectional questionnaire study (n=777). MethodsWomen were eligible if they were over 18, had been diagnosed with primary breast cancer, and had been prescribed tamoxifen. Participants were recruited in clinic or online and completed questionnaires assessing illness perceptions, treatment beliefs, adherence, quality of life, social support, distress, and the key TPB components. Logistic regressions were conducted to test elements from each model and to identify correlates of intentional and unintentional non-adherence. ResultsPatients were classified as non-adherent based on Medication Adherence Rating Scale scores; 44% of the population were non-adherent; 41% reported unintentional non-adherence, and 9% reported intentional non-adherence. Study variables accounted for more variance in intentional (Nagelkerke R-2=46%) than unintentional non-adherence (Nagelkerke R-2=17%). Intentional non-adherence was best explained by a combination of TPB and CSM variables, but these variables did not contribute significantly to unintentional non-adherence. ConclusionsThe TPB and the CSM provide a useful framework for understanding intentional tamoxifen non-adherence. Elements from both models should be considered when designing interventions to increase adherence rates.
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