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Digital tissue and what it may reveal about the brain

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BMC BIOLOGY
卷 15, 期 -, 页码 -

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BIOMED CENTRAL LTD
DOI: 10.1186/s12915-017-0436-9

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资金

  1. NIH/NINDS (High Resolution Connectomics of Mammalian Neural Circuits) [TR01 1R01NS076467, 1U01NS090449-01]
  2. NIMH Silvio Conte Center [1P50MH094271]
  3. IARPA via DoI/IBC [D16PC00002]
  4. MURI Army Research Office [W911NF1210594, IIS-1447786]
  5. U.S. Department of Defense (DOD) [W911NF1210594] Funding Source: U.S. Department of Defense (DOD)

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Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue digitization can actually reveal more than direct observation of tissue. One field where this transformation is occurring is connectomics: the mapping of neural connections in large volumes of digitized brain tissue.

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