Incidental Malignancies Identified During Staging for Prostate Cancer With 68Ga Prostate-specific Membrane Antigen HBED-CC Positron Emission Tomography Imaging

The rapid uptake of Ga-68 prostate-specific membrane antigen HBED-CC positron emission tomography (PSMA PET) imaging for prostate cancer staging has led to concerns regarding its specificity, with uptake in both malignant and nonmalignant tissues. We describe 3 separate malignancies identified on PSMA PET imaging. The misnomer prostatespecific membrane antigen is demonstrated by this case and highlights the importance of continued investigation of the potential role of PSMA PET in other malignancies. (C) 2017 Elsevier Inc.