期刊
CLINICS IN PLASTIC SURGERY
卷 44, 期 4, 页码 793-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cps.2017.05.010
关键词
Nerve compression syndromes; Peripheral neuropathy; Peripheral nerves
类别
资金
- Plastic Surgery Foundation
- American Association of Plastic Surgery Award
- American Association for the Surgery of Trauma
- American College of Surgeons Clowes Award
- Association of Academic Surgery
- [1K08GM109105-01]
Peripheral neuropathy and nerve compression syndromes lead to substantial morbidity following burn injury. Patients present with pain, paresthesias, or weakness along a specific nerve distribution or experience generalized peripheral neuropathy. The symptoms manifest at various times from within 1 week of hospitalization to many months after wound closure. Peripheral neuropathy may be caused by vascular occlusion of vasa nervorum, inflammation, neurotoxin production leading to apoptosis, and direct destruction of nerves from the burn injury. This article discusses the natural history, diagnosis, current treatments, and future directions for potential interventions for peripheral neuropathy and nerve compression syndromes related to burn injury.
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