期刊
ENDOSCOPY INTERNATIONAL OPEN
卷 5, 期 6, 页码 E505-E512出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0043-105492
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资金
- NCI NIH HHS [K07 CA160753] Funding Source: Medline
Background and study aims The optimal technique for sampling pancreatic lesions with a 22G Procore needle (pc) is unknown. The aims of this study were to evaluate the 22Gpc using standard suction technique (SST) and capillary suction technique (CST) and compare diagnostic adequacy of 22 Gpc with the standard 25G needle. Patients and methods Sixty consecutive patients referred for EUS-FNA of a solid pancreatic mass were prospectively evaluated. All patients underwent 2 passes with a standard 25G needle for cytologic analysis. The first group of 30 patients underwent a single pass with the 22Gpc needle using SST for cytology and histology. The second group underwent a single pass with the 22 Gpc needle using CST. The sequence of passes was randomized. The diagnostic adequacy of each pass was graded by 2 cytopathologists blinded to technique and needle type for comparison. Results For a cytologic diagnosis with 22Gpc, an adequate sample was obtained in 82.8% SST vs. 80.0% CST (P = 0.79). For a histologic diagnosis with 22Gpc, an adequate sample was obtained in 70.4% SST vs. 69.0% CST (P = 0.91). A single pass with 22 Gpc provided comparable results to a single pass with the 25G needle for a cytologic diagnosis; both were superior to a single 22 Gpc pass for a histologic diagnosis. Two passes with the 25G needle provided a diagnostic specimen in 95.0% vs 81.4% with one pass using 22 Gpc (P = 0.01). Conclusions No significant difference in diagnostic adequacy was observed between techniques for the 22 Gpc. Two passes with a 25G needle performed better than 1 pass with 22Gpc. (NCT01598194)
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