Effect of ginger and its nanoparticles on growth performance, cognition capability, immunity and prevention of motile Aeromonas septicaemia in Cyprinus carpio fingerlings

Novel study was performed to evaluate the efficacy of ginger (GN) and its nanoparticles (GNNP) on growth, cognition, immunity and prevention of motile Aeromonas septicaemia (MAS) in Cyprinus carpio fingerlings. Fish were divided into five groups fed diet 1 (control; no additives), diet 2 (0.5g of GN), 3 (1g of GN), 4 (0.5g of GNNP) and 5 (1g of GNNP) per kg feed for 30days. In the behavioural test, fish were individually placed in a foraging maze to evaluate their cognition capability and feeding behaviour. At the end of feeding period, fish fed GN and GNNP showed significant better final weight than the controls. GN and GNNP significantly increased total protein, globulin and lysozyme, whereas 1g GNNP group was the highest. One gram of GN, 0.5g and 1g GNNP enhanced cognition capability, while GN and GNNP increased percentage of fish fed in the maze. Brain acetylcholinesterase was significantly decreased than control in 1g GN group. GNNP succeeded in the prevention of MAS more than GN, because no mortalities and 100% relative percentage survival (RPS) were detected in 1 and 0.5g GNNP and 1g GN per kg feed, while fish fed 0.5g GN showed 20% mortalities and 71.4 RPS.