期刊
ACS NANO
卷 11, 期 12, 页码 11773-11776出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.7b08008
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资金
- Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology [CE140100036]
- Deutsche Forschungsgemeinschaft (DFG) [794/25-1]
- Australian Research Council
In this Perspective, we reflect on a decade of research on the protein corona and contemplate its broad implications for future science and engineering at the bio-nano interface. Specifically, we focus on the physical origins and time evolution of the protein corona, differences in the nanoparticle-protein entity in in vitro and in vivo environments, the role of stealth polymers to minimize the formation of the protein corona, relevant computational and theoretical developments, and the biocorona, a concept extrapolated from the field of nanomedicine. We conclude the Perspective by outlining future directions and opportunities concerning the protein corona in the coming decade.
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