期刊
PRECISION AND FUTURE MEDICINE
卷 1, 期 4, 页码 159-167出版社
SUNGKYUNKWAN UNIV SCH MEDICINE
DOI: 10.23838/pfm.2017.00184
关键词
Gram-negative bacteria; PmrAB; Polymyxins
Colistin is an old drug, and its use has recently resurged because of increasing antibiotic resistance in gram-negative bacteria such as Acinetobacter baumannii. Although the colistin resistance rates in gram-negative bacteria are currently not high, many colistin-resistant isolates are being identified and the possibility of horizontal transmission of colistin resistance has increased because of the plasmid-borne colistin resistance gene mcr-1 (mobilized colistin resistance). In this review, we have discussed colistin resistance in A. baumannii. In addition, we have reviewed an abnormal phenomenon called colistin dependence in A. baumannii.
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