期刊
CURRENT OPINION IN IMMUNOLOGY
卷 49, 期 -, 页码 64-70出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2017.10.002
关键词
-
类别
资金
- Ministry of Education, Culture, Sports, Science and Technology of Japan
- Japan Science and Technology Agency
- Grants-in-Aid for Scientific Research [16H06295] Funding Source: KAKEN
Treg cells expressing the transcription factor Foxp3 are essential for immunological tolerance and homeostasis. Recent genome-wide studies have revealed that Foxp3(+) natural Treg cells possess a number of unique transcriptional and epigenetic features, which appear to be acquired along the course of Treg cell development and maintained throughout their lifespan. These studies also provide novel insights into how genomic variations contribute to genetic susceptibility to human autoimmune diseases by affecting Treg cell development and function.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据