期刊
GELS
卷 3, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/gels3040036
关键词
poly(N-isopropylacrylamide); thermo-responsive polymer; copolymers; biocompatibility; biodegradability; 4D-printing
资金
- Ministry of Science and Innovation (MICINN)
- European Regional Development Fund (FEDER) funds from Ministry of Education, Culture and Sport of Spain [MAT2015-69367-R]
The innate ability of poly(N-isopropylacrylamide) (PNIPAAm) thermo-responsive hydrogel to copolymerize and to graft synthetic polymers and biomolecules, in conjunction with the highly controlled methods of radical polymerization which are now available, have expedited the widespread number of papers published in the last decade-especially in the biomedical field. Therefore, PNIPAAm-based hydrogels are extensively investigated for applications on the controlled delivery of active molecules, in self-healing materials, tissue engineering, regenerative medicine, or in the smart encapsulation of cells. The most promising polymers for biodegradability enhancement of PNIPAAm hydrogels are probably poly(ethylene glycol) (PEG) and/or poly(epsilon-caprolactone) (PCL), whereas the biocompatibility is mostly achieved with biopolymers. Ultimately, advances in three-dimensional bioprinting technology would contribute to the design of new devices and medical tools with thermal stimuli response needs, fabricated with PNIPAAm hydrogels.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据