期刊
TRIBOLOGY INTERNATIONAL
卷 109, 期 -, 页码 586-592出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.triboint.2017.01.038
关键词
Friction; Silk; Meniscus replacement; Cartilage; Lubricin
资金
- German Research Foundation [DFG DU254/7-1]
- German Armed Forces [E/U2AD/ED001/EF551]
- Wellcome Trust [100917/Z/13/Z]
- Innovate UK [101604, 102162]
- Wellcome Trust [100917/Z/13/Z] Funding Source: Wellcome Trust
- Innovate UK [102162, 101604] Funding Source: UKRI
The menisci protect the articular cartilage by reducing contact pressure in the knee. To restore their function after injury, a new silk fibroin replacement scaffold was developed. To elucidate its tribological properties, friction of the implant was tested against cartilage and glass, where the latter is typically used in tribological cartilage studies. The silk scaffold exhibited a friction coefficient against cartilage of 0.056, which is higher than meniscus against cartilage but in range of the requirements for meniscal replacements. Further, meniscus friction against glass was lower than cartilage against glass, which correlated with the surface lubricin content. Concluding, the tribological properties of the new material suggest a possible long-term chondroprotective function. In contrast, glass always produced high, non-physiological friction coefficients.
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