期刊
CURRENT OPINION IN CHEMICAL BIOLOGY
卷 41, 期 -, 页码 28-35出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2017.10.004
关键词
-
资金
- National Science Foundation [MCB-1330914]
- MIT-Portugal Program
Microbial cell factories are a renewable source for the production of biofuels and valuable chemicals. Dynamic pathway regulation has proved successful in improving production of molecules by balancing flux between growth of cells and production of metabolites. Systems for autonomous induction of pathway regulation are increasingly being developed, which include metabolite responsive promoters, biosensors, and quorum sensing systems. Since engineering such systems are dependent on the available methods for controlling protein abundance in the desired host, we review recent tools used for gene repression at the transcriptional, post -transcriptional and post-translational levels in Escherichia coli and Saccharomyces cerevisiae. These approaches may facilitate pathway engineering for biofuel and biochemical production.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据