期刊
COLLOIDS AND SURFACES B-BIOINTERFACES
卷 160, 期 -, 页码 325-330出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.colsurfb.2017.09.044
关键词
Chitosan; Hydrogels; Antibacterial properties; Cytotoxicity; Nanosilver
资金
- National Centre for Research and Development [LIDER/033/697/L-5/13/NCBR/2014]
Chitosan based hydrogels are commonly applied in various fields of medicine and pharmacy. Modification of hydrogel polymers using nanosilver particles may result in formation of materials with enhanced antibacterial properties. In this article synthesis of hydrogel materials based on chitosan and modified with silver nanoparticles is presented. First, preparation and characterization of silver nanoparticles using UV-vis spectroscopy has been shown. Hydrogels modified with nanosilver particles were subjected to the measurements of swelling ability and in vitro tests in distilled water and Simulated Body Fluid (SBF), respectively. Additionally, evaluation of antibacterial properties against Staphylococcus aureus and Enterococcus faecalis as well as results of cytotoxicity of hydrogel materials modified with silver nanoparticles conducted by means of XTT and MIT assays using dermis cells BJ (CRL-2522TM) have been presented. (C) 2017 Elsevier B.V. All rights reserved.
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