期刊
BIOINFORMATICS
卷 33, 期 23, 页码 3824-3826出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btx500
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资金
- Bill and Melinda Gates Foundation
- Collaboration for AIDS Vaccine Discovery [OPP1115782]
A Summary: The Electron Microscopy Hole Punch (EMHP) is a streamlined suite of tools for quick assessment, sorting and hole masking of electron micrographs. With recent advances in single-particle electron cryo-microscopy (cryo-EM) data processing allowing for the rapid determination of protein structures using a smaller computational footprint, we saw the need for a fast and simple tool for data pre-processing that could run independent of existing high-performance computing (HPC) infrastructures. EMHP provides a data preprocessing platform in a small package that requires minimal python dependencies to function.
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