期刊
TRENDS IN PLANT SCIENCE
卷 22, 期 11, 页码 949-960出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tplants.2017.08.006
关键词
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资金
- United States National Science Foundation [IOS-1444400, IOS-1339194, IOS-1453613]
- Department of Energy [DE-SC0012629]
- Oklahoma Center for the Advancement of Science and Technology [PS14-025]
- University of Oklahoma Research Council
- Direct For Biological Sciences [1444400] Funding Source: National Science Foundation
- Division Of Integrative Organismal Systems [1444400] Funding Source: National Science Foundation
- U.S. Department of Energy (DOE) [DE-SC0012629] Funding Source: U.S. Department of Energy (DOE)
Our understanding of plant biology is increasingly being built upon studies using 'omics and system biology approaches performed at the level of the entire plant, organ, or tissue. Although these approaches open new avenues to better understand plant biology, they suffer from the cellular complexity of the analyzed sample. Recent methodological advances now allow plant scientists to overcome this limitation and enable biological analyses of single-cells or single-cell-types. Coupled with the development of bioinformatics and functional genomics resources, these studies provide opportunities for high-resolution systems analyses of plant phenomena. In this review, we describe the recent advances, current challenges, and future directions in exploring the biology of single-cells and single-cell-types to enhance our understanding of plant biology as a system.
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