Structure and Enhanced Antifungal Activity of a Divalent Cobalt(II) Complex with Hexaconazole

A new Co-II complex, [CoL4Cl2]center dot 2CH(3)CH(2)OH(L=hexaconazole), was synthesized and characterized by means of elemental analysis, infrared spectroscopy and single-crystal X-ray diffraction. The crystal structural analysis shows that the centrosymmetric Co2+ is coordinated by four hexaconazole ligands and two Cl- to form a distorted octahedral geometry. The complex forms 1D chains through the intermolecular hydrogen bonds interaction of O-H center dot center dot center dot O and O-H center dot center dot center dot Cl. Furthermore, the antifungal activities of the complex against Grape anthracnose(I), Botryosphaeria berengriana(II), Botryosphaeria ribis(III) and Wheat gibberellic(IV) have been investigated and compared with those of the corresponding ligand. The results show that the complex has better antifungal activity than the ligand, which indicates that the coordination of the ligand and the metal enhances the antimicrobialactivity.