期刊
CURRENT OPINION IN NEUROBIOLOGY
卷 47, 期 -, 页码 73-79出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2017.09.015
关键词
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资金
- ERC CoG Grant
- German Research Foundation [SI 746/10-1, SFB1870, SPP1757, TRR43]
- Tschira-Stiftung
- ERA-NET 'Network for European Funding for Neuroscience Research' (NEURON
- BMBF Germany)
- Cluster of Excellence
- DFG Research Center SyNergy
The established function of oligodendrocytes and their progenitors is to drive the cellular events of myelination, a highly diversified process necessary to match the needs of various neuronal subtypes and networks. The morphological and molecular heterogeneity of oligodendrocytes and their progenitors point to functions beyond establishing saltatory nerve conduction. Here, we review the diversity in the oligodendroglial lineage as well as the classical and new functions identified for oligodendrocytes and their progenitors. Because oligodendroglia remain highly responsive to environmental changes, they likely contribute to various neurological and psychiatric diseases.
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