期刊
TRENDS IN CELL BIOLOGY
卷 27, 期 10, 页码 697-698出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2017.08.007
关键词
-
类别
资金
- Richard and Susan Smith Family Foundation
- Charles H. Hood Foundation
- Claudia Adams Barr Program for Innovative Cancer Research
- Cancer Research Institute CLIP Grant
DNA damage elicits a potent proinflammatory immune response. A collection of four papers now reveals that micronuclear DNA is a new cell intrinsic immunostimulatory molecule, and that accumulation of the immune sensor cyclic GMP-AMP synthase (cGAS) in micronuclei leads to a cell-cycle-dependent proinflammatory response following DNA damage.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据