期刊
TRENDS IN BIOTECHNOLOGY
卷 35, 期 9, 页码 824-835出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2017.02.003
关键词
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资金
- Agence Nationale de la Recherche [ANR-06-BLAN-0088, ANR-06-443 BDIV-006, ANR 09-GENM-033-001]
- CNRS/INSU-coordinated EC2CO program
- Metaprogramme MEM of the INRA (project Metascreen)
- Franco-Indian CEFIPRA center [4709-1]
- ANR-DFG [ANR-RF-2015-01]
- Agence Nationale de la Recherche (ANR) [ANR-06-BLAN-0088] Funding Source: Agence Nationale de la Recherche (ANR)
Eukaryotic microorganisms from diverse environments encompass a large number of taxa, many of them still unknown to science. One strategy to mine these organisms for genes of biotechnological relevance is to use a pool of eukaryotic mRNA directly extracted from environmental samples. Recent reports demonstrate that the resulting metatranscriptomic cDNA libraries can be screened by expression in yeast for a wide range of genes and functions from many of the different eukaryotic taxa. In combination with novel emerging high-throughput technologies, we anticipate that this approach should contribute to exploring the functional diversity of the eukaryotic microbiota.
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