期刊
TRAFFIC
卷 18, 期 7, 页码 425-432出版社
WILEY
DOI: 10.1111/tra.12488
关键词
bacteria; outer membrane vesicles; secretion system; virulence factor
类别
资金
- Estimulos al Desempeno en Investigacion
- Comision y Fomento de Actividades Academicas (Instituto Politecnico Nacional)
- Sistema Nacional de Investigadores (SNICONACyT)
- Secretaria de Investigacion y Posgrado del Instituto Politecnico Nacional (SIP) [20160609, 20161245, 20171714, 20171099]
Gram-negative bacteria have mechanisms through which they can colonize and survive in different environments, such as the secretion systems types (1-6) that have been widely studied and characterized. Nowadays, some authors have proposed extracellular structures, such as the outer membrane vesicles (OMVs), to be considered as an additional and independent secretion system. The OMVs are spherical particles of 50-250 nm in diameter; they originate in the outer membrane, and therefore they have a very similar composition to the latter. These particles can transport an important variety of biomolecules: enzymes, toxins, antigenic determinants and even nucleic acids. Thus, it is of great interest to collect data describing the advantages of the transport of biomolecules through the OMVs and, thus, determine their role as a potential secretion system.
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