4.3 Article

Concise Synthesis of Hydroxy β-Methyl Fatty Acid Ethyl Esters

期刊

CHEMICAL & PHARMACEUTICAL BULLETIN
卷 65, 期 12, 页码 1195-1198

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PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.c17-00637

关键词

beta-methyl fatty acid; chemical synthesis; Johnson-Claisen rearrangement; hydroxy fatty acid

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Hydroxy beta-methyl fatty acid ethyl esters bearing different carbon chain lengths and varying hydroxyl group positions were successfully synthesized from symmetric diols. These fatty acid derivatives are useful intermediates of chemical probes for metabolic analyses of fatty acid.

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