A highly selective HBT-based turn-on fluorescent probe for hydrazine detection and its application

As one of the important industrial chemicals, hydrazine (N2H4) can be inhaled through the skin, leading to many serious health issues. In this paper, we constructed a novel turn-on fluorescent probe HBTM for N2H4 detection based on ESIPT and ICT mechanism by incorporating the methyl dicyanvinyl group to 2(2'-hydroxylphenyl) benzothiazole (HBT) fluorophore. The probe showed the following advantages: high sensitivity with detection limit of 2.9 x 10(-7) M, high selectivity over other related interfering species, wide linear range of 0-140 M and pH value adaptation. Moreover, the probe could detect N2H4 on paper strips and image N2H4 in living cells. (C) 2017 Elsevier Ltd. All rights reserved.