期刊
TETRAHEDRON LETTERS
卷 58, 期 40, 页码 3897-3900出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.08.073
关键词
Taxus wallichiana; Taxaceae; Opened-oxetane ring; C-20 benzoyloxy; alpha-Glucosidase
资金
- Vietnam National University Ho Chi Minh City [A2015-18-02]
Two new taxanes, named wallitaxane G (1) and H (2), were isolated from the roots of Taxus wallichiana (Taxaceae), together with nine known compounds (3-11). Their structures were elucidated on the basis of NMR spectroscopic analysis and the relative configurations of 1 and 2 were determined based on NOESY data. Wallitaxane H (2) showed the most potent cc-glucosidase inhibitory activity, with an IC50 value of 16.1 M. Plausible biosynthetic pathways for the formation of 1 and 2 were proposed based on oxetane ring-opening and benzoyl migration. (C) 2017 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据