期刊
TETRAHEDRON LETTERS
卷 58, 期 20, 页码 1912-1916出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2017.02.090
关键词
Two component reaction; C-H functionalization; Iron-catalyzed; Benzylation; Quinoline
资金
- NSFC [21302178, 21325208, 21361140372, 21572212, 21502184]
- FANEDD [201424]
- FRFCU
- PCSIRT
- Youth Innovation Promotion Association of the Chinese Academy of Sciences [2015371]
An efficient and convenient method for C5-benzylation of quinoline frameworks is developed with the using of inexpensive FeCl3 catalyst. A range of N-bisbenzylic and N-monobenzylic sulfonamides smoothly react with aliphatic amides and aromatic amides, giving the corresponding products in moderate to excellent yields. (C) 2017 Published by Elsevier Ltd.
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