期刊
3RD CIRP CONFERENCE ON BIOMANUFACTURING
卷 65, 期 -, 页码 219-224出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.procir.2017.04.017
关键词
3D bioprinting; Tissue engineering; Hydrogel scaffolds
资金
- Research Science and Technology Department of Zhejiang Province [2013C33161]
- National Natural Science Foundation of China [81501607, 51475419]
- Natural Science Foundation of Zhejiang Province of China [LY15H160019]
- Key Research and Development Projects of Zhejiang Province [2017C1054]
Hydrogel scaffolds play vital roles in tissue engineering via providing appropriate microenvironments for cell adhesion, proliferation, and functioning. In this paper, a high-resolution 3D bioprinting system was developed for precise deposition of biomaterials mixed with cells, and thus, freeform fabrication of cell-laden hydrogel scaffolds. The feasibility of the system was validated by experiments. High cell viability was presented in live/dead assay. Cell aggregation and migration were observed after cultured for 2, 7, 14, and 21 days. Results indicated that the system had potential for fabricating cell-laden hydrogel scaffolds which could maintain high cellular activities. (C) 2016 The Authors. Published by Elsevier B.V.
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