Cationic Pd(II)-catalyzed arylative cyclization of N-(2-formylaryl) alkynamides: An efficient route to 2-quinolinones

A cationic palladium complex catalyzed arylative cyclization reaction of N-(2-formylaryl)alkynamides with arylboronic acids was developed. This new process provides an efficient way for the synthesis of functionalized 2-quinolinones in good to excellent yields under mild conditions. Some control experiments were conducted to explain the possible mechanism for the formation of the products. (C) 2017 Published by Elsevier Ltd.