期刊
TALANTA
卷 175, 期 -, 页码 427-434出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2017.07.078
关键词
Atomic layer deposition TiO2; TiO2-NH2; On-plate phosphopeptide/glycopeptide enrichment; Simultaneous enrichment; MALDI
资金
- National Natural Science Foundation of China [21425518, 21405022, 21675034]
- National Basic Research Priorities Program of China [2013CB911201]
In this work, a TiO2 film was prepared on a MALDI plate by atomic layer deposition (ALD) technique and then modified with -NH2. The obtained TiO2-NH2 modified plate was applied for on-plate simultaneous enrichment of phosphopeptides and glycopeptides. The ALD TiO2 film displayed quite uniform morphology, and attached firmly to the MALDI plate with rather stable physical and chemical properties, which resulted in fine stability of the plate in performance. The -NH2 groups offered the film better hydrophilicity and affinity toward glycopeptides. The on-plate simultaneous enrichment performance of the TiO2-NH2 modified plate was investigated by beta-casein digests, HRP digests and human serum.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据