4.3 Article

CAN-catalyzed microwave promoted reaction of indole with Betti bases under solvent-free condition and evaluation of antibacterial activity of the products

期刊

SYNTHETIC COMMUNICATIONS
卷 47, 期 21, 页码 2007-2014

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2017.1360912

关键词

Betti base; CAN-catalyzed; 3-(; -diarylmethyl)indoles; microwave; solvent-free

资金

  1. Science and Engineering Research Board (SERB), India [SB/FT/CS-073/2014]
  2. SERB, New Delhi, India [SB/FT/CS-100/2012]

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CAN-catalyzed reaction of Betti bases with indoles under microwave irradiation gives 3-(,-diarylmethyl)indoles. Better yield of the products, especially when one of the aryl ring is phenol were achieved. The reaction is performed in solvent-free condition. The antibacterial studies of the synthesized compounds were performed and some of the compounds showed good activity against Methicillin-resistant Staphylococcus aureus bacteria.

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