Total Syntheses of Atrovenetin and Atrovenetinone: A Naphtha-lene-Annulation Approach to a Discoid Tricycle Using Allenic Acid

A total synthesis of atrovenetin has been achieved. The discoid tricyclic motif was constructed by a novel three-carbon annulation of naphthalene derivative and allenic acid under acidic conditions. An effective protocol for the conversion of atrovenetin into atrovenetinone has been established.