期刊
SYNLETT
卷 29, 期 4, 页码 388-396出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1591839
关键词
asymmetric catalysis; enantioselective desymmetrization; dihydrosilanes; tetraorganosilanes; silicon stereocenters
资金
- Ministry of Education, Culture, Sports, Science and Technology, Japan [16H04145]
- Grants-in-Aid for Scientific Research [16H04145, 15K13688] Funding Source: KAKEN
It is highly important to develop efficient synthetic methods for various enantioenriched chiral compounds due to their high significance in our life. In this regard, asymmetric catalysis is one of the most attractive ways of synthesizing such compounds from achiral precursors. Although various methods have been developed for the enantioselective preparation of carbon-stereogenic compounds, the corresponding methods for silicon-stereogenic compounds are much less established. In particular, little progress has been made on catalytic enantioselective synthesis using prochiral organosilanes until recently. This account focuses on the recent progress in the catalytic enantioselective preparation of silicon-stereogenic organosilanes through desymmetrization of prochiral organosilanes. 1 Introduction 2 Desymmetrization of Diorganodihydrosilanes 3 Desymmetrization of Tetraorganosilanes 3.1 Desymmetrization through Cleavage of Silicon-Carbon Bonds 3.2 Desymmetrization without Cleavage of Silicon-Carbon Bonds 4 Conclusion
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据