期刊
CURRENT OPINION IN ELECTROCHEMISTRY
卷 5, 期 1, 页码 183-192出版社
ELSEVIER
DOI: 10.1016/j.coelec.2017.09.014
关键词
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资金
- Romanian National Authority for Scientific Research UEFISCDI [PN-II-RU-TE-2014-4-0460]
- Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Romania [7690/24/15.04.2016]
- DAAD fellowship [50015559]
- BMBF [FKZ: 13XP5007C]
Anomalous expression of miRNAs has been linked with cell cycles such as cell proliferation, stress response, differentiation, cell apoptosis and inflammation, which present a manifestation of multitude types of disorders and malignancies. For this reason, miRNAs became a class of biomarkers that is in the research focus in recent years. Their detection in an early stage of diseases represents a difficult challenge for analytical chemists who need to design not only specific but also highly sensitive tools for their detection. The progress achieved in the bio-electrochemical detection of miRNAs in the last 2 years is highlighted and commented, focusing on the applicability of developed strategies for point-of-care sensing.
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