期刊
STROKE
卷 48, 期 7, 页码 1916-+出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/STROKEAHA.116.016433
关键词
cognition; follow-up studies; music; randomized controlled trial; rehabilitation; stroke
资金
- Sten A Olsson Foundation for Research and Culture
- Swedish Brain Foundation
- Swedish Arts Council
- Swedish Governmental Program for Clinical Research
- AFA Insurance
- Swedish Stroke Association
- Rune and Ulla Amlov's Foundation for Neurological and Rheumatological Research
- Edith Jacobson Foundation
- Per-Olof Ahl Foundation for Neurological Research
- Sigurd and Elsa Goljes Memorial Foundation
- Wilhelm and Martina Lundgren Scientific Foundation
- Doktor Felix Neubergh's Foundation
- Swedish Society of Medicine
- Foundation for Rehabilitation and Medical Science
- Gladys M. Brawn Fund at University of Newcastle
Background and Purpose-Treatments that improve function in late phase after stroke are urgently needed. We assessed whether multimodal interventions based on rhythm-and-music therapy or horse-riding therapy could lead to increased perceived recovery and functional improvement in a mixed population of individuals in late phase after stroke. Methods-Participants were assigned to rhythm-and-music therapy, horse-riding therapy, or control using concealed randomization, stratified with respect to sex and stroke laterality. Therapy was given twice a week for 12 weeks. The primary outcome was change in participants' perception of stroke recovery as assessed by the Stroke Impact Scale with an intention-to-treat analysis. Secondary objective outcome measures were changes in balance, gait, grip strength, and cognition. Blinded assessments were performed at baseline, postintervention, and at 3-and6-month follow-up. Results-One hundred twenty-three participants were assigned to rhythm-and-music therapy (n=41), horse-riding therapy (n=41), or control (n=41). Post-intervention, the perception of stroke recovery ( mean change from baseline on a scale ranging from 1 to 100) was higher among rhythm-and-music therapy (5.2 [95% confidence interval, 0.79-9.61]) and horse-riding therapy participants (9.8 [95% confidence interval, 6.00-13.66]), compared with controls (-0.5 [-3.20 to 2.28]); P=0.001 (1-way ANOVA). The improvements were sustained in both intervention groups 6 months later, and corresponding gains were observed for the secondary outcomes. Conclusions-Multimodal interventions can improve long-term perception of recovery, as well as balance, gait, grip strength, and working memory in a mixed population of individuals in late phase after stroke.
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