期刊
STEM CELL RESEARCH
卷 25, 期 -, 页码 18-21出版社
ELSEVIER
DOI: 10.1016/j.scr.2017.10.004
关键词
-
资金
- Medical faculty of Heinrich-Heine University Dusseldorf
- Bundesministerium fur Wirtschaft und Energie (BMWi) [FKZ: ZF4047101AJ5]
SIX2-positive renal cells isolated from urine from a 51 year old male of African origin bearing the CYP2D6 *4/*17 variant were reprogrammed by nucleofection of a combination of two episomal-based plasmids omitting pathway (TGF beta, MEK and GSK3 beta) inhibition. The induced pluripotent stemcells (iPSCs) were characterized by immunocytochemistry, embryoid body formation, DNA-fingerprinting and karyotype analysis. Comparative transcriptome analyses with human embryonic stem cell lines H1 and H9 revealed a Pearson correlation of 0.9243 and 0.9619 respectively. (c) 2017 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.
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