A novel chromogenic and fluorogenic scaffold for detection of oxidative radicals

Radical detection has attracted significant attention recently. Here we have developed a scaffold through covalent assembly principle (OR570), which could facile applications in detection of oxidative radicals. The primary advantage of the assembly type probe lies at the turn-on fluorescence signal from a zero background and hence high fluorescence turn-on ratio for sensitive detection of weak signal. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.