UV and fluorescent spectra study the reaction between 1, 8-Naphthalimide derivative and hypochlorite their applications

Two simple, efficient turn-on fluorescent probes for hypochlorite have been rationally designed and developed by utilizing the oxidation of hypochlorite. Notably, probe 1 and 2 displayed rapid and remarkable turn-on responses to ClO- in PBS buffer solution (pH 7.4). Further, the optical properties of two probes and their ClO--addition products were confirmed by density functional theory calculations. And detection limits of two probes for ClO- based on the definition by IUPAC were calculated for 2.882 nM and 0354 mu M. More importantly, cell imaging experiments demonstrated that probe 1 was more suitable for detecting the ClO- in living A549 cells. And both two probes had the possibility of potentially applied in practical applications such as detecting the hypo chlorite concentration of tap water and river water. (C) 2016 Elsevier B.V. All rights reserved.