期刊
SLEEP MEDICINE
卷 39, 期 -, 页码 87-94出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.sleep.2017.07.027
关键词
Diabetes mellitus; Dyslipidemias; Holidays; Hypertension; Longitudinal studies; Obesity
资金
- Japanese Ministry of Health Labor and Welfare [H25-JUNKANKITOU-IPPAN-007]
Background: This longitudinal study investigated the effects of various lifestyle-related factors - including sleep duration, shift work, and actual days taken off work - on new-onset metabolic syndrome (MetS). Methods and results: A total of 39,182 male employees (mean age 42.4 +/- 9.8 years) of a local government organization in Japan were followed up for a maximum of seven years, between 1999 and 2006. Multivariate analysis (Cox proportional hazard method) identified seven high-risk lifestyle factors that were significantly associated with new-onset MetS or a range of metabolic factors (obesity, hypertension, hyperglycemia, dyslipidemia): (1) short sleep duration (<5 h/day), (2) shift work, (3) insufficient number of days off work, (4) always eating until satiety, (5) not trying to take every opportunity to walk, (6) alcohol intake >= 60 g/day, and (7) smoking. In addition, a higher number of these high-risk lifestyle factors significantly promoted the onset of MetS. The hazard ratio for MetS associated with 0-1 high-risk lifestyle parameters per subject at the baseline was set at 1.00. Hazard ratios associated with the following numbers of high-risk lifestyle parameters were: 1.22 (95% CI 1.15-1.29) for 2-3 of these parameters; and 1.43 (1.33-1.54) for 4-7. Conclusion: An increase in the number of high-risk lifestyle factors - such as short sleep duration, shift work, and an insufficient number of days off work - increased the risk of MetS onset. Comprehensive strategies to improve a range of lifestyle factors for workers, such as sleep duration and days off work, could reduce the risk of MetS onset. (C) 2017 Elsevier B.V. All rights reserved.
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