期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 56, 期 35, 页码 10564-10568出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201705467
关键词
cyclodextrins; hydroformylation; mechanosynthesis; regioselectivity; supramolecular chemistry
资金
- Chevreul Institute [FR 2638]
- Ministere de l'Enseignement Superieur et de la Recherche
- Region Nord-Pas de Calais
- FEDER
The Rh-catalyzed hydroformylation of aromatic substituted alkenes is performed in a planetary ball mill under CO/H-2 pressure. The dispersion of the substrate molecules and the Rh-catalyst into the grinding jar is ensured by saccharides: methyl-alpha-D-glucopyranoside, acyclic dextrins, or cyclodextrins (CDs, cyclic oligosaccharides). The reaction affords the exclusive formation of aldehydes whatever the saccharide. Acyclic saccharides disperse the components within the solid mixture leading to high conversions of alkenes. However; they showed typical selectivity for alpha-aldehyde products. If CDs are the dispersing additive, the steric hindrance exerted by the CDs on the primary coordination sphere of the metal modifies the selectivity so that the beta-aldehydes were also formed in non negligible proportions. Such through-space control via hydrophobic effects over reactivity and regioselectivity reveals the potential of such solventless process for catalysis in solid state.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据