Ecological Considerations of Per- and Polyfluoroalkyl Substances (PFAS)

Per- and polyfluoroalkyl substances (PFASs) have been detected around the globe in drinking water, in various media at release sites, in human blood serum, and in non-human biota tissue. These compounds are emerging contaminants due to the rapidly evolving regulatory landscape, which is driven by advances in toxicological and risk assessment knowledge emanating from academia and government research organizations. A robust understanding of these developments is required to appreciate the basis, present state, and future direction of regulation and management of PFASs. This paper summarizes recent toxicological and ecological risk assessment information, ongoing research, and current guide-lines governing PFASs for the protection of non-human biota.