3.8 Article

A simple simulator to teach enzyme kinetics dynamics. Application in a problem-solving exercise

期刊

HIGHER EDUCATION PEDAGOGIES
卷 2, 期 1, 页码 14-27

出版社

ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/23752696.2017.1307693

关键词

Enzyme kinetics; Michaelis-Menten model; SIMENKIN; problem-solving approach; biosciences

资金

  1. MINECO [BIO2014-54411-C2-2-R]
  2. DISENO MATEMATICO DE ESTRATEGIAS PARA LA INGENIERIA METABOLICA DE CEPAS DE E. COLI COMO PLATAFORMA PARA BIO-RUTAS SINTETICAS ROBUSTAS [BIO2014-54411-C2-2-R]

向作者/读者索取更多资源

Enzyme kinetics is an essential part of biochemistry programs, which have been gaining importance in recent years for their applications in biotechnology and biomedicine. The teaching and learning of these issues has been traditionally hampered by difficulties that stem mainly from the dynamic and mathematical nature of the topic and the introduction of some abstract concepts. In this paper, we propose a simple, home-made application developed in Excel or, alternatively, in Libre Office (SIMENKIN), which allows students to view and interact with the dynamics of enzymatic reactions. The contribution of this specific application stems from the simulation of substrate loss and the associated initial rate of the enzyme catalysed reaction overtime, which is not always incorporated into these packages. We illustrate its use applying it in a practical problem-solving approach module, designed to facilitate the learning of the fundamental concepts of enzyme kinetics.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

3.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据